Lake Superior State University
Lake Superior State University
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Alum Success

Rachael graduated from Novi High School in Novi, Michigan. Rachael completed their senior research project by developing a method of detecting blastomyces dermatitidis in soil using PCR. This study lays the foundation for further studying blastomyces dermatitidis in soil samples from endemic regions in northern Michigan. Rachael is a member of the Alpha Chi Honor Society. Rachael recently was selected to go to MSU to train in qPCR techniques and assisted in their cow bacteroides project. Rachael plans to attend graduate school in the future to study biochemistry.

Rachael Cunningham
2010 Outstanding Graduate
Forensic Chemistry

Department of Environmental Sciences

Facilities & Equipment

Chemical Instrumentation



16 GIS workstations with Arc GIS 10.1 & 36 inch poster plotter

Professional GPS Hardware


Field Sampling Equipment

Van Dorn bottles, flow meters, Hydrolab multiparamer sonde, Ponar dredge, drum samplers, battery powered sampling pumps, etc.

Hiltunen Field Station

~40 Acres with shoreline on Sugar Island in the St. Marys River

Synthesis of Multicyclic Products ...

Josh Brown

“Synthesis of Multicyclic Products from Annulation Reaction of an Imadazoline and β-Hydroxy Carboxylic Acids”: Imidazolines are nitrogen containing hetercycles that can be found in natural products. They have unique properties particularly their ability to react with electrophiles and nucleophiles. If reacted with a molecule that contains both, imidazolines can undergo annulations to produce many interesting products. This study attempted to prepare a multicyclic product from the reaction of 1-benzyl-2-phenyl-2-imidazoline with salicyloyl chloride or salicylic acid under three different conditions to determine which was optimal. The first reaction is a two step process that uses salicyloyl chloride produced from salicylic acid. The salicyloyl chloride is then used in an annulations reaction with the imidazoline. Production of salicyloyl chloride by known methods failed. Conditions two and three attempted a similar annulations using the coupleing reagents BOP-Cl and EDC with salicylic acid and the imidazoline. These reagents work to bond the carboxylic acid to the imidazoline N and make the reaction one step. The EDC reaction failed to produce the right product, the BOP-Cl reaction appeared successful based on GCMS. However, during the purification the product was not able to be isolated.

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